I have two things to say about this.
First, every aspiring Indie developer should set this comic as their screensaver, so that it flashes up at any moment when you are foolish enough to feel hope.
Second, I love the term "Indie games" because it doesn't have all the Loser connotations that "shareware" did. I now realize that it's only a matter of time before "Indie game" gets all the same connotations.
If you don't believe me, drop by XNA Community games (Soon to be XBox Live Indie Games. Thanks Microsoft!) and try those out. (Shudder.)